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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $469 | 10-14 weeks | |
25 mg | $1,670 | 10-14 weeks | |
50 mg | $2,180 | 10-14 weeks | |
100 mg | $3,480 | 10-14 weeks | |
1 mL x 10 mM (in DMSO) | $739 | 10-14 weeks |
Description | MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively). |
In vivo | In the lipid utilization analysis, MGAT2-IN-1 significantly increases free fatty acid (FFA) and acylcarnitine levels. MGAT2-IN-1 (30 mg/kg) also significantly reduces food intake dose dependently, suppresses BW gains. MGAT2-IN-1 shows anti-diabetic effects in mice[1]. |
Molecular Weight | 654.01 |
Formula | C27H21ClF5N7O3S |
Cas No. | 1800025-30-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 125 mg/mL (191.13 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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