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Midaglizole

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Catalog No. T68098Cas No. 66529-17-7
Alias DG5128 free base, (±)-DG5128 free base

Midaglizole ((±)-DG5128 free base, DG5128 free base) is a potent α2-adrenoceptor antagonist that acts as a hypoglycemic agent by lowering blood glucose levels and increasing blood pressure in vivo.

Midaglizole

Midaglizole

😃Good
Catalog No. T68098Alias DG5128 free base, (±)-DG5128 free baseCas No. 66529-17-7
Midaglizole ((±)-DG5128 free base, DG5128 free base) is a potent α2-adrenoceptor antagonist that acts as a hypoglycemic agent by lowering blood glucose levels and increasing blood pressure in vivo.
Pack SizePriceAvailabilityQuantity
25 mg$1,4001-2 weeks
50 mg$1,8201-2 weeks
100 mg$2,5001-2 weeks
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Product Introduction

Bioactivity
Description
Midaglizole ((±)-DG5128 free base, DG5128 free base) is a potent α2-adrenoceptor antagonist that acts as a hypoglycemic agent by lowering blood glucose levels and increasing blood pressure in vivo.
In vitro
dTRIM24 suppresses growth, accompanied by apoptosis measured as enhanced PARP cleavage.[1]
dTRIM24 is a TRIM24 bromodomain degrader.[1]
Recruitment of the VHL E3 ubiquitin ligase by dTRIM24 elicits potent and selective degradation of TRIM24.[1]
AliasDG5128 free base, (±)-DG5128 free base
Chemical Properties
Molecular Weight251.33
FormulaC16H17N3
Cas No.66529-17-7
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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