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ML233 is a potent non-peptide apelin receptor agonist (EC50 = 3.7 μM) that exhibits more than 21-fold selectivity over the closely related angiotensin 1 receptor (AT1) (>79 μM) [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,140 | 6-8 weeks | |
50 mg | $2,785 | 6-8 weeks | |
100 mg | $3,520 | 6-8 weeks |
Description | ML233 is a potent non-peptide apelin receptor agonist (EC50 = 3.7 μM) that exhibits more than 21-fold selectivity over the closely related angiotensin 1 receptor (AT1) (>79 μM) [1]. |
In vitro | ML233 demonstrates a potentially significant affinity for various receptors, such as the 5-HT1A, α2C adrenergic, and benzylpiperazine receptors, in addition to the norepinephrine transporter. However, ML233 exhibits a degree of toxicity (LC 50 =25.8 μM) towards human hepatocytes [1]. |
Molecular Weight | 359.44 |
Formula | C19H21NO4S |
Cas No. | 2080311-92-6 |
Storage | Shipping with blue ice. |
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