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Description | MLK-IN-1 (US20140256733A1, compound 68) is a highly potent and selective inhibitor of mixed lineage kinase 3 (MLK-3). It exhibits excellent brain penetration and specifically targets MLK-3. |
In vitro | MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes axon growth and provides protection against HIV-Tat's harmful effects, even when microglia are activated by Tat, in vitro[1]. |
Molecular Weight | 432.5 |
Formula | C23H20N4O3S |
Cas No. | 1627729-62-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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