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MLK-IN-1

🥰Excellent
Catalog No. T39102Cas No. 1627729-62-7

MLK-IN-1 (US20140256733A1, compound 68) is a highly potent and selective inhibitor of mixed lineage kinase 3 (MLK-3). It exhibits excellent brain penetration and specifically targets MLK-3.

MLK-IN-1

MLK-IN-1

🥰Excellent
Catalog No. T39102Cas No. 1627729-62-7
MLK-IN-1 (US20140256733A1, compound 68) is a highly potent and selective inhibitor of mixed lineage kinase 3 (MLK-3). It exhibits excellent brain penetration and specifically targets MLK-3.
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Product Introduction

Bioactivity
Description
MLK-IN-1 (US20140256733A1, compound 68) is a highly potent and selective inhibitor of mixed lineage kinase 3 (MLK-3). It exhibits excellent brain penetration and specifically targets MLK-3.
In vitro
MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes axon growth and provides protection against HIV-Tat's harmful effects, even when microglia are activated by Tat, in vitro[1].
Chemical Properties
Molecular Weight432.5
FormulaC23H20N4O3S
Cas No.1627729-62-7
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

MLK-IN-1MLKIN1MLK IN 1
Related Tags: buy MLK-IN-1 | purchase MLK-IN-1 | MLK-IN-1 cost | order MLK-IN-1 | MLK-IN-1 chemical structure | MLK-IN-1 in vitro | MLK-IN-1 formula | MLK-IN-1 molecular weight
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