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MLT-747

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Catalog No. T16119Cas No. 2097853-86-4

MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).

MLT-747

MLT-747

😃Good
Catalog No. T16119Cas No. 2097853-86-4
MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).
Pack SizePriceAvailabilityQuantity
25 mg$1,1406-8 weeks
50 mg$1,4906-8 weeks
100 mg$2,3606-8 weeks
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Product Introduction

Bioactivity
Description
MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).
Targets&IC50
MALT1:14 nM
In vitro
MLT-747 (0-20 μM) stabilizes cellular MALT1-W580S with an EC50 of 314 nM.
Chemical Properties
Molecular Weight478.33
FormulaC20H21Cl2N7O3
Cas No.2097853-86-4
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

MLT747MLT-747MLT 747
Related Tags: buy MLT-747 | purchase MLT-747 | MLT-747 cost | order MLT-747 | MLT-747 chemical structure | MLT-747 in vitro | MLT-747 formula | MLT-747 molecular weight
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