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MMV008138

Name: MMV008138
Brand: TargetMol
SKU: T12084
Price: 50 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T12084Cas No. 1679333-73-3

MMV008138 inhibits the growth of P. falciparum Dd2 strain (IC50 of 250 nM).

MMV008138

😃Good

Catalog No. T12084Cas No. 1679333-73-3

MMV008138 inhibits the growth of P. falciparum Dd2 strain (IC50 of 250 nM).

Pack Size	Price	Availability
5 mg	$446	6-8 weeks
25 mg	$1,430	6-8 weeks
50 mg	$1,860	6-8 weeks
100 mg	$2,500	6-8 weeks
1 mL x 10 mM (in DMSO)	$432	6-8 weeks

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Product Introduction

Bioactivity

Description	MMV008138 inhibits the growth of P. falciparum Dd2 strain (IC50 of 250 nM).
Targets&IC50	PfIspD:44 nM
In vitro	MMV008138 targets IspD enzymes in the MEP pathway of P. falciparum[1]

Chemical Properties

Molecular Weight	361.22
Formula	C₁₈H₁₄Cl₂N₂O₂
Cas No.	1679333-73-3
Relative Density.	1.473 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 125 mg/mL (346.05 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7684 mL	13.8420 mL	27.6840 mL	138.4198 mL
5 mM	0.5537 mL	2.7684 mL	5.5368 mL	27.6840 mL
10 mM	0.2768 mL	1.3842 mL	2.7684 mL	13.8420 mL
20 mM	0.1384 mL	0.6921 mL	1.3842 mL	6.9210 mL
50 mM	0.0554 mL	0.2768 mL	0.5537 mL	2.7684 mL
100 mM	0.0277 mL	0.1384 mL	0.2768 mL	1.3842 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MMV-008138MMV 008138MMV008138