Shopping Cart

Remove All

Your shopping cart is currently empty

Mps1-IN-1

Select Batch

Purity:97.78%

Resource Download

COA HNMR HPLC LCMS

Mps1-IN-1

Catalog No. T12102Cas No. 1125593-20-5

Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$90	In Stock
10 mg	$169	In Stock
25 mg	$333	In Stock
50 mg	$498	In Stock
100 mg	$723	In Stock
1 mL x 10 mM (in DMSO)	$107	In Stock

Bulk & Custom

Add to Cart

Questions

Product Introduction

Bioactivity

Description	Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )
In vitro	Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase(IC50 and a Kd of 367 nM and 27 nM). Mps1-IN-1 also has high affinity for ALK, and LTK, with Kds of 21 and 39 nM, respectively[1].

Chemical Properties

Molecular Weight	535.66
Formula	C28H33N5O4S
Cas No.	1125593-20-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 39 mg/mL (72.81 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8669 mL	9.3343 mL	18.6686 mL	93.3428 mL
5 mM	0.3734 mL	1.8669 mL	3.7337 mL	18.6686 mL
10 mM	0.1867 mL	0.9334 mL	1.8669 mL	9.3343 mL
20 mM	0.0933 mL	0.4667 mL	0.9334 mL	4.6671 mL
50 mM	0.0373 mL	0.1867 mL	0.3734 mL	1.8669 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc