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Mt KARI-IN-2

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Catalog No. T61570Cas No. 2413974-52-2

Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. It also inhibits Mtb H37Rv with a MIC value of 0.78 μM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 μg/mL [1].

Mt KARI-IN-2

Mt KARI-IN-2

😃Good
Catalog No. T61570Cas No. 2413974-52-2
Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. It also inhibits Mtb H37Rv with a MIC value of 0.78 μM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 μg/mL [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. It also inhibits Mtb H37Rv with a MIC value of 0.78 μM and demonstrates low cytotoxicity, as indicated by a HEK IC50 greater than 86 μg/mL [1].
Chemical Properties
Molecular Weight377.4
FormulaC14H11N5O4S2
Cas No.2413974-52-2
Storage & Solubility Information
StorageShipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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