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Mt KARI-IN-4 (compound 5c) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki of 5.48 μM. It also inhibits Mtb H37Rv, displaying a minimum inhibitory concentration (MIC) of 0.78 μM, and exhibits low cytotoxicity, with an IC50 over 72 μg/mL against human embryonic kidney cells (HEK) [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Mt KARI-IN-4 (compound 5c) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki of 5.48 μM. It also inhibits Mtb H37Rv, displaying a minimum inhibitory concentration (MIC) of 0.78 μM, and exhibits low cytotoxicity, with an IC50 over 72 μg/mL against human embryonic kidney cells (HEK) [1]. |
Molecular Weight | 365.36 |
Formula | C13H8FN5O3S2 |
Cas No. | 2413974-53-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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