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Mt KARI-IN-5

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Catalog No. T62081Cas No. 2413974-69-1

Mt KARI-IN-5 (compound 6c) was a potent inhibitor of Mycobacterium tuberculosis ketohydrin reductase I (MtbKARI) (Ki: 4.72 μM), exhibited inhibition of MtbH37Rv activity with a MIC value of 1.56 μM, showed low cytotoxicity, and had an IC50 value for HEK greater than 64 μg/mL.

Mt KARI-IN-5

Mt KARI-IN-5

😃Good
Catalog No. T62081Cas No. 2413974-69-1
Mt KARI-IN-5 (compound 6c) was a potent inhibitor of Mycobacterium tuberculosis ketohydrin reductase I (MtbKARI) (Ki: 4.72 μM), exhibited inhibition of MtbH37Rv activity with a MIC value of 1.56 μM, showed low cytotoxicity, and had an IC50 value for HEK greater than 64 μg/mL.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
Mt KARI-IN-5 (compound 6c) was a potent inhibitor of Mycobacterium tuberculosis ketohydrin reductase I (MtbKARI) (Ki: 4.72 μM), exhibited inhibition of MtbH37Rv activity with a MIC value of 1.56 μM, showed low cytotoxicity, and had an IC50 value for HEK greater than 64 μg/mL.
Chemical Properties
Molecular Weight410.45
FormulaC14H10N4O5S3
Cas No.2413974-69-1
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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