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MTX-PEG-Cy3
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Catalog No. T203560
MTX-PEG-Cy3 is a Cy3-labeled MTX-PEG conjugate. Cy3 fluorophore is frequently utilized in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a maximum emission wavelength of approximately 562-570 nm. Methotrexate (Amethopterin; MTX) serves as an antimetabolite and antifolate agent that inhibits dihydrofolate reductase, preventing the conversion of folic acid to tetrahydrofolate and ultimately inhibiting DNA synthesis. Additionally, Methotrexate functions as an immunosuppressant and antineoplastic agent, deployed in the treatment of rheumatoid arthritis and the investigation of various cancers, including acute lymphoblastic leukemia.
MTX-PEG-Cy3
MTX-PEG-Cy3
😃Good
Catalog No. T203560
MTX-PEG-Cy3 is a Cy3-labeled MTX-PEG conjugate. Cy3 fluorophore is frequently utilized in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a maximum emission wavelength of approximately 562-570 nm. Methotrexate (Amethopterin; MTX) serves as an antimetabolite and antifolate agent that inhibits dihydrofolate reductase, preventing the conversion of folic acid to tetrahydrofolate and ultimately inhibiting DNA synthesis. Additionally, Methotrexate functions as an immunosuppressant and antineoplastic agent, deployed in the treatment of rheumatoid arthritis and the investigation of various cancers, including acute lymphoblastic leukemia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Chemical Properties
| Description | MTX-PEG-Cy3 is a Cy3-labeled MTX-PEG conjugate. Cy3 fluorophore is frequently utilized in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a maximum emission wavelength of approximately 562-570 nm. Methotrexate (Amethopterin; MTX) serves as an antimetabolite and antifolate agent that inhibits dihydrofolate reductase, preventing the conversion of folic acid to tetrahydrofolate and ultimately inhibiting DNA synthesis. Additionally, Methotrexate functions as an immunosuppressant and antineoplastic agent, deployed in the treatment of rheumatoid arthritis and the investigation of various cancers, including acute lymphoblastic leukemia. |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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