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MurA-IN-1

Name: MurA-IN-1
Brand: TargetMol
SKU: T35877
Price: 39 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T35877Cas No. 354815-90-0

MurA-IN-1 (compound 1a), a PTPRR inhibitor, exhibits IC50 values of 0.09 μM for PTPRR, 0.23 μM for PTP1B, 0.75 μM for PTPN7, and 0.8 μM for PTPN5, respectively, targeting a family of human MAPK-specific protein tyrosine phosphatases[1].

MurA-IN-1

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Catalog No. T35877Cas No. 354815-90-0

Pack Size	Price	Availability
25 mg	Inquiry	6-8 weeks
50 mg	Inquiry	6-8 weeks
100 mg	Inquiry	6-8 weeks

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Product Introduction

Bioactivity

Description	MurA-IN-1 (compound 1a), a PTPRR inhibitor, exhibits IC50 values of 0.09 μM for PTPRR, 0.23 μM for PTP1B, 0.75 μM for PTPN7, and 0.8 μM for PTPN5, respectively, targeting a family of human MAPK-specific protein tyrosine phosphatases[1].
Targets&IC50	PTPN7:0.75 μM (IC50), PTP1B:0.23 μM (IC50), PTPN5:0.8 μM (IC50), PTPRR:0.09 μM (IC50)

Chemical Properties

Molecular Weight	215.25
Formula	C₁₃H₁₃NO₂
Cas No.	354815-90-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (232.29 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6458 mL	23.2288 mL	46.4576 mL	232.2880 mL
5 mM	0.9292 mL	4.6458 mL	9.2915 mL	46.4576 mL
10 mM	0.4646 mL	2.3229 mL	4.6458 mL	23.2288 mL
20 mM	0.2323 mL	1.1614 mL	2.3229 mL	11.6144 mL
50 mM	0.0929 mL	0.4646 mL	0.9292 mL	4.6458 mL
100 mM	0.0465 mL	0.2323 mL	0.4646 mL	2.3229 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MurA-IN-1MurAIN1MurA IN 1