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Myxochelin A is a microbial metabolite found in *A. disciformis* with diverse biological activities. It exhibits activity against Gram-positive bacteria, including *B. cereus*, *S. aureus*, and *M. luteus*, but not against Gram-negative bacteria or fungi at a concentration of 80 μg/disc in an agar diffusion assay. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity, with an IC50 value of 1.9 μM for the recombinant human enzyme. Additionally, it is cytotoxic to 26-L5 colon cancer cells at a concentration of 3 μg/ml.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $960 | 35 days |
Description | Myxochelin A is a microbial metabolite found in *A. disciformis* with diverse biological activities. It exhibits activity against Gram-positive bacteria, including *B. cereus*, *S. aureus*, and *M. luteus*, but not against Gram-negative bacteria or fungi at a concentration of 80 μg/disc in an agar diffusion assay. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity, with an IC50 value of 1.9 μM for the recombinant human enzyme. Additionally, it is cytotoxic to 26-L5 colon cancer cells at a concentration of 3 μg/ml. |
Molecular Weight | 404.419 |
Formula | C20H24N2O7 |
Cas No. | 120243-02-9 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Methanol: Soluble Ethanol: Soluble DMSO: Soluble |
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