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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | N-(Azido-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker that incorporates an azido group and two PEG3-acid moieties. This compound is widely applicable in the synthesis of proteolysis targeting chimeras (PROTACs), which are molecules with the ability to selectively degrade target proteins[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 626.69 |
Formula | C26H50N4O13 |
Cas No. | 2055042-57-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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