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N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5

Name: N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5
Brand: TargetMol
SKU: T18426
Rating: 4.5 (1 reviews)

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Catalog No. T18426Cas No. 2107273-78-7

N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker commonly used in PROTAC synthesis [1].

N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5

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Catalog No. T18426Cas No. 2107273-78-7

N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker commonly used in PROTAC synthesis [1].

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Product Introduction

Bioactivity

Description	N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker commonly used in PROTAC synthesis [1].
In vitro	PROTACs consist of two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase and the other targets the specific protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins [1].

Chemical Properties

Molecular Weight	1185.95
Formula	C₆₁H₉₃ClN₆O₁₃S
Cas No.	2107273-78-7
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PEGsN(mPEG4)N'(BiotinPEG2amidoPEG4)Cy5N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5N-(m-PEG-4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5N (m PEG4) N' (Biotin PEG2 amido PEG4) Cy5

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