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N-acetyl-S-geranylgeranyl-L-Cysteine

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Catalog No. T37693Cas No. 139332-94-8

N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.

N-acetyl-S-geranylgeranyl-L-Cysteine

N-acetyl-S-geranylgeranyl-L-Cysteine

😃Good
Catalog No. T37693Cas No. 139332-94-8
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Pack SizePriceAvailabilityQuantity
1 mgInquiry35 days
5 mgInquiry35 days
10 mgInquiry35 days
25 mgInquiry35 days
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Product Introduction

Bioactivity
Description
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
Chemical Properties
Molecular Weight435.67
FormulaC25H41NO3S
Cas No.139332-94-8
Relative Density.1.013 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 33 mg/mL (75.75 mM), Sonication is recommended.
DMF: 50 mg/mL (114.77 mM), Sonication is recommended.
Ethanol: 50 mg/mL (114.77 mM), Sonication is recommended.
0.1 M Na2CO3: 11 mg/mL (25.25 mM), Sonication is recommended.
Solution Preparation Table
0.1 M Na2CO3/DMSO/DMF/Ethanol
1mg5mg10mg50mg
1 mM2.2953 mL11.4766 mL22.9532 mL114.7658 mL
5 mM0.4591 mL2.2953 mL4.5906 mL22.9532 mL
10 mM0.2295 mL1.1477 mL2.2953 mL11.4766 mL
20 mM0.1148 mL0.5738 mL1.1477 mL5.7383 mL
DMSO/DMF/Ethanol
1mg5mg10mg50mg
50 mM0.0459 mL0.2295 mL0.4591 mL2.2953 mL
DMF/Ethanol
1mg5mg10mg50mg
100 mM0.0230 mL0.1148 mL0.2295 mL1.1477 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-acetyl-S-geranylgeranyl-L-CysteineN acetyl S geranylgeranyl L CysteineNacetylSgeranylgeranylLCysteine
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