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N-butyryl-L-Homocysteine thiolactone

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Catalog No. T37342Cas No. 202284-85-3

N-butyryl-L-Homocysteine thio-lactone, an analog of N-butyryl-L-homoserine lactone, is a small diffusible signaling molecule involved in quorum sensing for controlling gene expression and cellular metabolism. It induces violacein expression in C. violaceum mutants usually not able to produce acylhomoserine lactone (AHL), regulating genes like LuxIR family transcriptional regulators.

N-butyryl-L-Homocysteine thiolactone

N-butyryl-L-Homocysteine thiolactone

😃Good
Catalog No. T37342Cas No. 202284-85-3
N-butyryl-L-Homocysteine thio-lactone, an analog of N-butyryl-L-homoserine lactone, is a small diffusible signaling molecule involved in quorum sensing for controlling gene expression and cellular metabolism. It induces violacein expression in C. violaceum mutants usually not able to produce acylhomoserine lactone (AHL), regulating genes like LuxIR family transcriptional regulators.
Pack SizePriceAvailabilityQuantity
5 mgInquiry35 days
10 mgInquiry35 days
25 mgInquiry35 days
50 mgInquiry35 days
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Product Introduction

Bioactivity
Description
N-butyryl-L-Homocysteine thio-lactone, an analog of N-butyryl-L-homoserine lactone, is a small diffusible signaling molecule involved in quorum sensing for controlling gene expression and cellular metabolism. It induces violacein expression in C. violaceum mutants usually not able to produce acylhomoserine lactone (AHL), regulating genes like LuxIR family transcriptional regulators.
Chemical Properties
Molecular Weight187.26
FormulaC8H13NO2S
Cas No.202284-85-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 50 mg/mL (267.01 mM), Sonication is recommended.
Ethanol: 25 mg/mL (133.5 mM), Sonication is recommended.
DMSO: 30 mg/mL (160.21 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (2.67 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/Ethanol/DMSO/DMF
1mg5mg10mg50mg
1 mM5.3402 mL26.7008 mL53.4017 mL267.0084 mL
Ethanol/DMSO/DMF
1mg5mg10mg50mg
5 mM1.0680 mL5.3402 mL10.6803 mL53.4017 mL
10 mM0.5340 mL2.6701 mL5.3402 mL26.7008 mL
20 mM0.2670 mL1.3350 mL2.6701 mL13.3504 mL
50 mM0.1068 mL0.5340 mL1.0680 mL5.3402 mL
100 mM0.0534 mL0.2670 mL0.5340 mL2.6701 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N butyryl L Homocysteine thiolactoneNbutyrylLHomocysteine thiolactoneN-butyryl-L-Homocysteine thiolactone
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