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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly used in synthesizing proteolysis-targeting chimeras (PROTACs) [1].
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Description | N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly used in synthesizing proteolysis-targeting chimeras (PROTACs) [1]. |
In vitro | PROTACs, composed of two distinct ligands connected by a linker—one for an E3 ubiquitin ligase and the other for the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | n-methyl-n-methyl-o-m-peg4-o-propargyl-peg4-cy5 |
Molecular Weight | 855.5 |
Formula | C47H67ClN2O10 |
Cas No. | 2107273-50-5 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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