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N-Decanoyl cyclopentylamide (C10-CPA) serves as a potent quorum sensing inhibitor in Pseudomonas aeruginosa, disrupting the expression of virulence factors governed by both the las and rhl systems. It effectively suppresses the production of elastase, pyocyanin, rhamnolipid, and hinders biofilm formation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | N-Decanoyl cyclopentylamide (C10-CPA) serves as a potent quorum sensing inhibitor in Pseudomonas aeruginosa, disrupting the expression of virulence factors governed by both the las and rhl systems. It effectively suppresses the production of elastase, pyocyanin, rhamnolipid, and hinders biofilm formation. |
In vitro | N-Decanoyl cyclopentylamide (C10-CPA) inhibits quorum sensing in Pseudomonas aeruginosa, with half-maximal inhibitory concentrations for lasB-lacZ and rhlA-lacZ expression at 80 μM and 90 μM, respectively [1]. It also suppresses the production of virulence factors such as elastase, pyocyanin, rhamnolipids, and biofilm formation without affecting the growth of Pseudomonas aeruginosa PAO1 [1]. N-Decanoyl cyclopentylamide interferes with the las and rhl quorum sensing systems by disrupting the interaction between their response regulators (LasR and RhlR) and autoinducers [1]. |
Alias | C10-CPA |
Molecular Weight | 239.40 |
Formula | C15H29NO |
Cas No. | 540796-75-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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