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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $448 | 35 days |
Description | N-didesmethyl Loperamide, an active metabolite of the peripheral μ1-opioid receptor agonist loperamide, impedes electrically induced contractions in isolated guinea pig myenteric plexus (IC50 = 370 nM) and enhances the sensitivity of a chloroquine-resistant P. falciparum strain to chloroquine (EC50 = 482 nM). Notably, it achieves this without causing toxicity in A-10 vascular smooth muscle cells (IC50 = >10,000 nM). |
Alias | R 21345 |
Molecular Weight | 448.98 |
Formula | C27H29ClN2O2 |
Cas No. | 66164-06-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | Acetonitrile: slightly soluble Chloroform: sparingly soluble |
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