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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2500 μg | $2,660 | 35 days |
Description | Neoaureothin, a bacterial metabolite found in Streptomyces, is an androgen receptor (AR) antagonist that inhibits dihydrotestosterone (DHT) binding to ARs (IC50 = 13 μM) and DHT-induced prostate-specific antigen expression in LNCaP cells (IC50 = 1.75 nM). It is cytotoxic to A549, HCT116, and HepG2 cells (IC50s = 34.3, 47, and 37.2 μg/ml, respectively), exhibits nematocidal activity against the pine wood nematode B. xylophilus (LC50 = 0.84 μg/ml), and increases survival of P. densiflora trees inoculated with B. xylophilus. |
Molecular Weight | 477.557 |
Formula | C28H31NO6 |
Cas No. | 59795-94-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | Methanol: Soluble DMF: Soluble DMSO: Soluble Ethanol: Soluble |
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