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Neridronate

Name: Neridronate
Brand: TargetMol
SKU: T13794
Price: 45 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T13794Cas No. 79778-41-9

Neridronate is an aminobisphosphonate,for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB).

Neridronate

🥰Excellent

Catalog No. T13794Cas No. 79778-41-9

Neridronate is an aminobisphosphonate,for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB).

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Neridronate is an aminobisphosphonate,for the treatment of osteogenesis imperfecta (OI) and Paget’s disease of bone (PDB).

Chemical Properties

Molecular Weight	277.15
Formula	C₆H₁₇NO₇P₂
Cas No.	79778-41-9
Relative Density.	1.658 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 18.75 mg/mL (67.65 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.6082 mL	18.0408 mL	36.0815 mL	180.4077 mL
5 mM	0.7216 mL	3.6082 mL	7.2163 mL	36.0815 mL
10 mM	0.3608 mL	1.8041 mL	3.6082 mL	18.0408 mL
20 mM	0.1804 mL	0.9020 mL	1.8041 mL	9.0204 mL
50 mM	0.0722 mL	0.3608 mL	0.7216 mL	3.6082 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Neridronate