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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor. NF-κB-IN-5 interacts directly with NF-κB. NF-κB-IN-5 shows antitumor activity against human cancer cell lines, with IC 50 values of 5.35, 2.81, 2.83, 2.02 and 3.90 μM for HCT116, U87-MG, HepG2, BGC823, PC9, respectively. |
In vivo | NF-κB-IN-5, administered orally at a dosage of 40.0 mg/kg daily for 12 days to C57BL/6 mice bearing MC38 colon tumors, demonstrates significant antitumor efficacy [1]. |
Molecular Weight | 409.48 |
Formula | C23H27N3O4 |
Cas No. | 2425675-52-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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