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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $33 | Backorder |
Description | NH-bis(PEG3-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 537.68 |
Formula | C26H51NO10 |
Cas No. | 1814901-03-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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