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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | NH2-PEG8-C1-Boc is a PEG-based linker utilized in PROTACs, which connects two essential ligands for the formation of PROTAC molecules, facilitating selective protein degradation by exploiting the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are compounds with two ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other binds the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 483.59 |
Formula | C22H45NO10 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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