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Nifeviroc

🥰Excellent
Catalog No. T28171Cas No. 934740-33-7
Alias TD-0232, TD0232

Nifeviroc (TD-0232) is an orally active CCR5 antagonist used in the study of HIV-1 infection.

Nifeviroc

Nifeviroc

🥰Excellent
Purity: 98.14%
Catalog No. T28171Alias TD-0232, TD0232Cas No. 934740-33-7
Nifeviroc (TD-0232) is an orally active CCR5 antagonist used in the study of HIV-1 infection.
Pack SizePriceAvailabilityQuantity
1 mg$143 In Stock
5 mg$355 In Stock
10 mg$529 In Stock
25 mg$846 In Stock
50 mg$1,460 In Stock
100 mg$1,550 In Stock
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Purity:98.14%
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Product Introduction

Bioactivity
Description
Nifeviroc (TD-0232) is an orally active CCR5 antagonist used in the study of HIV-1 infection.
Targets&IC50
CHO cells:2.9 nM
In vitro
Nifeviroc is a specific HIV-1 entry inhibitor that works only by antagonizing CCR5 and not CXCR4. [1]
AliasTD-0232, TD0232
Chemical Properties
Molecular Weight590.71
FormulaC33H42N4O6
Cas No.934740-33-7
SmilesO[C@@]1(C2=CC=CC=C2)[C@H](CN(C1)C(C3CCCC3)=O)CN4CCC(CC4)N(CC=C)C(OCC5=CC=C(C=C5)[N+]([O-])=O)=O
Relative Density.1.28 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (135.43 mM), Sonication is recommended.
H2O: 80 mg/mL (135.43 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM1.6929 mL8.4644 mL16.9288 mL84.6439 mL
5 mM0.3386 mL1.6929 mL3.3858 mL16.9288 mL
10 mM0.1693 mL0.8464 mL1.6929 mL8.4644 mL
20 mM0.0846 mL0.4232 mL0.8464 mL4.2322 mL
50 mM0.0339 mL0.1693 mL0.3386 mL1.6929 mL
100 mM0.0169 mL0.0846 mL0.1693 mL0.8464 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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