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Nivocasan

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Catalog No. T68390Cas No. 908253-63-4

Nivocasan, also known as GS-9450 and LB-84451, a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. GS-9450 treatment induced significant reductions in ALT levels in NASH patients.

Nivocasan

Nivocasan

😃Good
Catalog No. T68390Cas No. 908253-63-4
Nivocasan, also known as GS-9450 and LB-84451, a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. GS-9450 treatment induced significant reductions in ALT levels in NASH patients.
Pack SizePriceAvailabilityQuantity
25 mg$1,9701-2 weeks
50 mg$2,5801-2 weeks
100 mg$3,4001-2 weeks
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Product Introduction

Bioactivity
Description
Nivocasan, also known as GS-9450 and LB-84451, a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. GS-9450 treatment induced significant reductions in ALT levels in NASH patients.
Chemical Properties
Molecular Weight415.41
FormulaC21H22FN3O5
Cas No.908253-63-4
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

GS-9450LB84451NivocasanLB 84451LB-84451GS9450
Related Tags: buy Nivocasan | purchase Nivocasan | Nivocasan cost | order Nivocasan | Nivocasan chemical structure | Nivocasan formula | Nivocasan molecular weight
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