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NLRP3-IN-12

Catalog No. T73034

NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome that targets the NLRP3 protein to effectively reduce IL-1β release, with an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease (IBD).

NLRP3-IN-12

NLRP3-IN-12

Catalog No. T73034
NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome that targets the NLRP3 protein to effectively reduce IL-1β release, with an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease (IBD).
Pack SizePriceAvailabilityQuantity
25 mg$1,520Backorder
50 mg$1,980Backorder
100 mg$2,500Backorder
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Product Introduction

Bioactivity
Description
NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome that targets the NLRP3 protein to effectively reduce IL-1β release, with an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease (IBD).
Chemical Properties
Molecular Weight518
FormulaC27H32ClNO7
Storage & Solubility Information
StorageShipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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