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NU5455

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Catalog No. T64204Cas No. 1257235-99-6

NU5455 is a selective, potent, orally active inhibitor of DNA-PKcs. It enhances the efficacy of locally released doxorubicin in liver tumor xenografts without causing adverse effects and also enhances the efficacy and toxicity of parenterally administered topoisomerase inhibitors.

NU5455

NU5455

😃Good
Catalog No. T64204Cas No. 1257235-99-6
NU5455 is a selective, potent, orally active inhibitor of DNA-PKcs. It enhances the efficacy of locally released doxorubicin in liver tumor xenografts without causing adverse effects and also enhances the efficacy and toxicity of parenterally administered topoisomerase inhibitors.
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
NU5455 is a selective, potent, orally active inhibitor of DNA-PKcs. It enhances the efficacy of locally released doxorubicin in liver tumor xenografts without causing adverse effects and also enhances the efficacy and toxicity of parenterally administered topoisomerase inhibitors.
Chemical Properties
Molecular Weight595.71
FormulaC34H33N3O5S
Cas No.1257235-99-6
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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