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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
10 mg | Inquiry | Backorder |
Description | Nusinersen, an antisense oligonucleotide drug, modifies the pre-messenger RNA (pre-mRNA) splicing of the SMN2 gene, thereby enhancing the production of the full-length Survival Motor Neuron (SMN) protein. |
In vitro | Nusinersen, an SMN-ASO, enhances SMN levels by inhibiting an intronic splice silencer within SMN2. This action promotes the inclusion of exon 7, leading to the production of full-length SMN2 transcripts[2]. |
Cas No. | 1258984-36-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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