Name: Obtusol
Brand: TargetMol
SKU: T125180
Rating: 4.5 (1 reviews)

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1 mg

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5 mg

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QHow to deal with the insoluble impurities in the product?

AInsoluble impurities, which do not affect the product activity, are recommended to filter out or remove. We will investigate to confirm whether the impurity was introduced during packaging or if it is inherent to the product itself.

QWhether TargetMol inhibitor products are suitable for industrial use?

AThere are various standards for defining the purity, and we do not have fixed purity standard. The purity of most products are above 98% and can be used for control experiments, including cell experiments, animal experiments, general laboratory experiments, and high-throughput screening. Our product purity also meets the industrial standard.

QWhat should I do if the products in powder form adhere to the vial tightly?

AIt's recommended to centrifuge it at 3000 rpm for a few minutes.

QThe detection results after adding the drug show no effect. Does this indicate a problem with the product quality?

AThe product quality is assured, All products have undergone two rigorous quality inspections. Structural confirmation is achieved through HNMR, while purity is determined by HPLC. However, the same inhibitor may yield different IC50 values and experimental outcomes due to variations in experimental materials (such as cells or animals). Therefore, it's not advisable to directly replicate methods in literature. Instead, establish concentration gradients tailored to your own experiments.

QCan the inhibitor DMSO stock solution be directly diluted with buffer to create a gradient?

AIn most cases, it can dissolve. However, sometimes organic reagents may precipitate when directly added to an aqueous medium. It is recommended to first dilute the inhibitor with DMSO to form a gradient, and then add the diluted inhibitor to the buffer or cell culture medium. Some inhibitors may only dissolve in the aqueous phase at their working concentrations. For example, if a final concentration of 1 μM is desired in cell experiments, the 10 mM DMSO stock solution can be diluted to 1 mM with DMSO, and then 2 μL can be drawn and added to 2 mL of saline/PBS/cell culture medium, resulting in a final concentration of 1 μM. To avoid precipitation of the drug, it is recommended to preheat the mother liquor and culture medium to 37°C before dilution to avoid serious precipitation caused by low temperature. If precipitation occurs during the dilution process, it is suggested to use ultrasonic heating to redissolve the compound.

Product Introduction

Bioactivity

Description

Obtusol is a natural product that can be used as a reference standard. The CAS number of Obtusol is 260392-01-6.

Chemical Properties

Molecular Weight	442.728
Formula	C₃₀H₅₀O₂
Cas No.	260392-01-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.