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Odatroltide
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Catalog No. T39121Cas No. 1639303-73-3
Alias Odatroltide, DHDMIQK(KAP)
Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus.
Odatroltide
😃Good
Catalog No. T39121Alias Odatroltide, DHDMIQK(KAP)Cas No. 1639303-73-3
Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $970 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus. |
| In vitro | Odatroltide (1 nM) proficiently diminishes P-selectin expression, paralleled by its ability to inhibit platelet aggregation - an effect also seen with DHDMIQK(KAP) through similar down-regulation of P-selectin. Furthermore, Odatroltide impedes platelet clumping triggered by TH, AA, ADP, and PAF, attributing its efficacy to P-selectin downregulation and free radical scavenging[1]. |
| In vivo | Odatroltide (0.01 nmol/kg) effectively lyses thrombi and inhibits thrombosis with minimal[1]. |
| Alias | Odatroltide, DHDMIQK(KAP) |
| Molecular Weight | 661.801 |
| Formula | C32H51N7O8 |
| Cas No. | 1639303-73-3 |
| Relative Density. | 1.249 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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