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ODN 1585
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Catalog No. T64277Cas No. 386832-46-8
ODN 1585 is a potent inducer of IFN and TNFα production, a robust stimulator of NK (natural killer) cells, and can be used as a vaccine adjuvant. It enhances the function of CD8+ T cells, including CD8+ T cell-mediated IFN-γ production, induces regression of established melanomas in mice, and has been shown to inhibit malaria in mice. Additionally, ODN 1585 can be used to study acute myelogenous leukemia (AML) and malaria.
ODN 1585
😃Good
Catalog No. T64277Cas No. 386832-46-8
ODN 1585 is a potent inducer of IFN and TNFα production, a robust stimulator of NK (natural killer) cells, and can be used as a vaccine adjuvant. It enhances the function of CD8+ T cells, including CD8+ T cell-mediated IFN-γ production, induces regression of established melanomas in mice, and has been shown to inhibit malaria in mice. Additionally, ODN 1585 can be used to study acute myelogenous leukemia (AML) and malaria.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $2,650 | 10-14 weeks | |
| 50 mg | $3,990 | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | ODN 1585 is a potent inducer of IFN and TNFα production, a robust stimulator of NK (natural killer) cells, and can be used as a vaccine adjuvant. It enhances the function of CD8+ T cells, including CD8+ T cell-mediated IFN-γ production, induces regression of established melanomas in mice, and has been shown to inhibit malaria in mice. Additionally, ODN 1585 can be used to study acute myelogenous leukemia (AML) and malaria. |
| Cas No. | 386832-46-8 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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