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OICR-0547

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Catalog No. T12290Cas No. 1801873-49-3

OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule Wdr5-MLL interaction antagonist.

OICR-0547

OICR-0547

😃Good
Catalog No. T12290Cas No. 1801873-49-3
OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule Wdr5-MLL interaction antagonist.
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2 mg$605 days
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Product Introduction

Bioactivity
Description
OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule Wdr5-MLL interaction antagonist.
Chemical Properties
Molecular Weight542.55
FormulaC28H29F3N4O4
Cas No.1801873-49-3
Relative Density.1.358 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (184.31 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8431 mL9.2157 mL18.4315 mL92.1574 mL
5 mM0.3686 mL1.8431 mL3.6863 mL18.4315 mL
10 mM0.1843 mL0.9216 mL1.8431 mL9.2157 mL
20 mM0.0922 mL0.4608 mL0.9216 mL4.6079 mL
50 mM0.0369 mL0.1843 mL0.3686 mL1.8431 mL
100 mM0.0184 mL0.0922 mL0.1843 mL0.9216 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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