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Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase (ACAT), an intracellular cholesteryl ester synthase involved in dietary cholesterol absorption, with an IC50 of 7 nM. When administered at 0.05% to rabbits or rats on a high fat, high cholesterol diet, it reduces low-density lipoproteins and increases high-density lipoprotein levels.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $85 | 35 days | |
10 mg | $160 | 35 days | |
50 mg | $660 | 35 days |
Description | Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase (ACAT), an intracellular cholesteryl ester synthase involved in dietary cholesterol absorption, with an IC50 of 7 nM. When administered at 0.05% to rabbits or rats on a high fat, high cholesterol diet, it reduces low-density lipoproteins and increases high-density lipoprotein levels. |
Molecular Weight | 441.744 |
Formula | C30H51NO |
Cas No. | 140112-65-8 |
Relative Density. | 0.919 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMF: 30 mg/mL Ethanol: 30 mg/mL PBS (pH 7.2): 1 mg/mL DMSO: 30 mg/mL |
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