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Omzotirome
🥰Excellent
Catalog No. T38483Cas No. 1092551-88-6
Alias TRC-150094
Omzotirome (TRC150094) is a functional analog of iodothyronines and holds potential for research on hyperlipidemia (WO2008149379).
Omzotirome
🥰Excellent
Catalog No. T38483Alias TRC-150094Cas No. 1092551-88-6
Omzotirome (TRC150094) is a functional analog of iodothyronines and holds potential for research on hyperlipidemia (WO2008149379).
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Product Introduction
Bioactivity
Chemical Properties
| Description | Omzotirome (TRC150094) is a functional analog of iodothyronines and holds potential for research on hyperlipidemia (WO2008149379). |
| In vivo | Omzotirome (0.750 mg/100 g; i.p.) administration in male Wistar rats (8 weeks old) on a high-fat diet (HFD) markedly reduces visceral adipose tissue compared to HFD counterparts, simultaneously altering metabolism in two metabolically active major tissues. This results in enhanced energy expenditure and fatty acid oxidation, culminating in body weight gain similar to rats fed a standard chow. Omzotirome acts as a functional analog of iodothyronines, effectively decreasing adiposity by boosting metabolic rates in response to a high-fat dietary intake[1]. |
| Alias | TRC-150094 |
| Molecular Weight | 328.412 |
| Formula | C19H24N2O3 |
| Cas No. | 1092551-88-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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