QWhy can't I see anything in the vial when I receive small-sized products?
ADue to the small pack, the powder may be highly dispersed during shipping due to static electricity and may adhere to the vial. Please centrifuge and add an appropriate solvent to fully dissolve the product and prepare the stock solution.
QAnimals cannot tolerate DMSO well. How should the dosage of DMSO be controlled during administration?
AFor normal mice, the concentration of DMSO should be kept below 10%. For nude mice, transgenic mice, or mice with weak tolerance, the concentration of DMSO should be kept below 2%. For inhibitors being used for the first time, it is recommended to perform a solvent-negative control experiment to confirm that the solvent has no nonspecific effects on the animals.
QCan high-temperature sterilization be used for inhibitors?
AMost products are synthesized by chemical methods
Qwhat frequency should sonication be used?
AIt is recommended to use the conventional ultrasound cleaning frequency
QCan PEG400 be used instead of PEG300?
APEG300 has moderate viscosity, which facilitates the dissolution and administration of drugs, while also providing good tolerability without adverse effects on animals. PEG400 can replace PEG300.
PEG600 is not very recommended because its melting point is close to room temperature.