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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 1-2 weeks | |
50 mg | $1,980 | 1-2 weeks | |
100 mg | $2,500 | 1-2 weeks |
Description | OTS186935 trihydrochloride, a protein methyltransferase inhibitor of SUV39H2, has an IC50 of 6.49 nM. |
Targets&IC50 | SUV39H2:6.49 nM |
In vitro | OTS186935 trihydrochloride, revealed significant inhibition of tumor growth in mouse xenograft models using MDA-MB-231 breast cancer cells and A549 lung cancer cells without any detectable toxicity.??SUV39H2 inhibitors sensitize cancer cells to DOX by reduction of γ-H2AX levels in cancer cells |
In vivo | OTS186935 trihydrochloride?exhibits growth suppressive effects in human cancer cell line derived xenograft models[1]. |
Molecular Weight | 573.34 |
Formula | C25H29Cl4N5O2 |
Cas No. | 2093401-85-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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