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p-APMSF (hydrochloride)

Name: p-APMSF (hydrochloride)
Brand: TargetMol
SKU: T37019
Rating: 4.5 (1 reviews)

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Catalog No. T37019Cas No. 74938-88-8

p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 μM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.

p-APMSF (hydrochloride)

😃Good

Catalog No. T37019Cas No. 74938-88-8

Pack Size	Price	Availability
1 mg	$83	35 days
5 mg	$223	35 days
10 mg	$392	35 days
25 mg	$890	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	252.69
Formula	C₈H₁₀ClFN₂O₂S
Cas No.	74938-88-8
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (197.87 mM), Sonication is recommended.

H2O: 25 mg/mL (98.94 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9574 mL	19.7871 mL	39.5742 mL	197.8709 mL
5 mM	0.7915 mL	3.9574 mL	7.9148 mL	39.5742 mL
10 mM	0.3957 mL	1.9787 mL	3.9574 mL	19.7871 mL
20 mM	0.1979 mL	0.9894 mL	1.9787 mL	9.8935 mL
50 mM	0.0791 mL	0.3957 mL	0.7915 mL	3.9574 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0396 mL	0.1979 mL	0.3957 mL	1.9787 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

pAPMSF (hydrochloride)p APMSF (hydrochloride)p-APMSF