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p32 Inhibitor M36

Catalog No. T16423Cas No. 802555-85-7

p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.

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Pack Size	Price	Availability	Quantity
2 mg	$89	5 days
100 mg	$997	6-8 weeks

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Product Introduction

Bioactivity

Description	p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
In vitro	p32 Inhibitor M36 is selective for p32 overexpressing cells. p32 Inhibitor M36 inhibits SF188 glioma cell proliferation (IC50: 77.9 μM in complete media) and is much more potent under low glucose conditions (IC50: 7.3 μM). p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres (IC50: 2.8 μM)[1].
Alias	M36

Chemical Properties

Molecular Weight	448.52
Formula	C23H28N8O2
Cas No.	802555-85-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5 mg/mL (11.15 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2296 mL	11.1478 mL	22.2955 mL	111.4777 mL
5 mM	0.4459 mL	2.2296 mL	4.4591 mL	22.2955 mL
10 mM	0.2230 mL	1.1148 mL	2.2296 mL	11.1478 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

M-36p32 Inhibitor M36p-32 Inhibitor M36M 36