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p32 Inhibitor M36
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Catalog No. T16423Cas No. 802555-85-7
Alias M36
p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
p32 Inhibitor M36
😃Good
Catalog No. T16423Alias M36Cas No. 802555-85-7
p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $89 | 5 days | |
| 100 mg | $997 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | p32 inhibitor M36 is an inhibitor of p32 mitochondrial protein. It binds directly to p32 and inhibits the p32 association with LyP-1. |
| In vitro | p32 Inhibitor M36 is selective for p32 overexpressing cells. p32 Inhibitor M36 inhibits SF188 glioma cell proliferation (IC50: 77.9 μM in complete media) and is much more potent under low glucose conditions (IC50: 7.3 μM). p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres (IC50: 2.8 μM)[1]. |
| Alias | M36 |
| Molecular Weight | 448.52 |
| Formula | C23H28N8O2 |
| Cas No. | 802555-85-7 |
| Relative Density. | 1.39 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (11.15 mM), Sonication and heating to 80℃ are recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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