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PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $108 | 35 days | |
5 mg | $468 | 35 days | |
10 mg | $830 | 35 days | |
25 mg | $1,800 | 35 days |
Description | PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP. |
Molecular Weight | 221.26 |
Formula | C14H11N3 |
Cas No. | 943902-10-1 |
Relative Density. | 1.246 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | Ethanol: 2 mg/mL (9.04 mM), Sonication is recommended. DMSO: 10 mg/mL (45.2 mM), Sonication is recommended. DMF: 10 mg/mL (45.2 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL (2.26 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Ethanol/DMSO/DMF
DMSO/DMF
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