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Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to elucidate the physiological role of gastrin, have therapeutic potential as acid antisecretory drugs, and may be of use as adjuvant therapy for gastrin sensitive tumours. The agonist effect of PD-136,450 is mediated via interaction with the gastrin (CCK-B) receptor in the stomach and the CCK-A receptor in the pancreas.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,870 | 10-14 weeks | |
50 mg | $3,780 | 10-14 weeks | |
100 mg | $5,200 | 10-14 weeks |
Description | Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to elucidate the physiological role o |
Alias | PD-136450, PD136450, Cam-1189, Cam1189, Cam 1189 |
Molecular Weight | 612.72 |
Formula | C35H40N4O6 |
Cas No. | 139067-52-0 |
Relative Density. | 1.33g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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