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PEG2000-C-DMG

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Catalog No. T74405Cas No. 1019000-64-6

PEG2000-C-DMG, a pegylated lipid, facilitates the creation of Onpattro, a hepatically targeted investigational RNAi therapeutic that effectively decreases the synthesis of both mutant and wild-type transthyretin by precisely targeting the 3′ untranslated region of transthyretin mRNA [1] [2].

PEG2000-C-DMG

PEG2000-C-DMG

😃Good
Catalog No. T74405Cas No. 1019000-64-6
PEG2000-C-DMG, a pegylated lipid, facilitates the creation of Onpattro, a hepatically targeted investigational RNAi therapeutic that effectively decreases the synthesis of both mutant and wild-type transthyretin by precisely targeting the 3′ untranslated region of transthyretin mRNA [1] [2].
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2 mg$735 days
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Product Introduction

Bioactivity
Description
PEG2000-C-DMG, a pegylated lipid, facilitates the creation of Onpattro, a hepatically targeted investigational RNAi therapeutic that effectively decreases the synthesis of both mutant and wild-type transthyretin by precisely targeting the 3′ untranslated region of transthyretin mRNA [1] [2].
Chemical Properties
Molecular Weight2610.29
FormulaC126H249NO52
Cas No.1019000-64-6
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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