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PGDM

Name: PGDM
Brand: TargetMol
SKU: T38257
Rating: 4.5 (1 reviews)

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Catalog No. T38257Cas No. 133161-96-3

Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2.

PGDM

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Catalog No. T38257Cas No. 133161-96-3

Pack Size	Price	Availability
25 μg	Inquiry	35 days
50 μg	Inquiry	35 days
100 μg	Inquiry	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	328.36
Formula	C₁₆H₂₄O₇
Cas No.	133161-96-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

PBS (pH 7.2): 1 mg/mL (3.05 mM), Sonication is recommended.

DMF: 50 mg/mL (152.27 mM), Sonication is recommended.

Ethanol: 50 mg/mL (152.27 mM), Sonication is recommended.

DMSO: 50 mg/mL (152.27 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0454 mL	15.2272 mL	30.4544 mL	152.2719 mL

DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
5 mM	0.6091 mL	3.0454 mL	6.0909 mL	30.4544 mL
10 mM	0.3045 mL	1.5227 mL	3.0454 mL	15.2272 mL
20 mM	0.1523 mL	0.7614 mL	1.5227 mL	7.6136 mL
50 mM	0.0609 mL	0.3045 mL	0.6091 mL	3.0454 mL
100 mM	0.0305 mL	0.1523 mL	0.3045 mL	1.5227 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PGDM