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Phainanoid A

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Catalog No. T81497Cas No. 1643933-50-9

Phainanoid A is a distinctive triterpenoid of the dammarane type.

Phainanoid A

Phainanoid A

😃Good
Catalog No. T81497Cas No. 1643933-50-9
Phainanoid A is a distinctive triterpenoid of the dammarane type.
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Questions
QWhat’s pIC50?
ApIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
QWhat’s EC50?
AHalf maximal effective concentratioin(EC50) refers to the concentration of a compound that achieves 50% of the maximum effect(inhibitory/stimulatory effect),after a specified exposure duration.
QWhat’s Ki?
AInhibitory consent (Ki) reflects the strength of inhibitor binding to the target, corresponding to the concentration of free inhibitor when 50% of the target is bound by the inhibitor.
QHow to recommend specific or broad-spectrum inhibitors for a target? What is the difference between specificity and nonspecificity?
AInhibitors can be classified into two types based on specificity: broad-spectrum (pan) and selective inhibitors. Pan inhibitors are inhibitors of a particular target that have inhibitory effects on all subtypes or members of the entire family. Selective inhibitors have particularly high inhibitory rates or specific inhibitory effects on a subtype of a protein kinase or a member of a family of proteins. The evaluation of the inhibitory efficiency of an inhibitor generally relies on the IC50 value, with lower IC50 values indicating higher inhibitory efficiency. We recommend considering the above characteristics comprehensively when selecting inhibitors, and you can also contact our technical team for recommendations on relevant inhibitors.
QWhat’s IC50?
AHalf-maximal inhibitory concentration (IC50) refers to the concentration of the inhibitor which is required to inhibit a given biological or biochemical function by half.
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Product Introduction

Bioactivity
Description
Phainanoid A is a distinctive triterpenoid of the dammarane type.
Chemical Properties
Molecular Weight626.74
FormulaC38H42O8
Cas No.1643933-50-9
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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