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Picoprazole

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Catalog No. T12471Cas No. 78090-11-6

Picoprazole is a specific H+/K+-ATPase inhibitor (IC50 of 3.1±0.4 μM).

Picoprazole

Picoprazole

😃Good
Catalog No. T12471Cas No. 78090-11-6
Picoprazole is a specific H+/K+-ATPase inhibitor (IC50 of 3.1±0.4 μM).
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
Picoprazole is a specific H+/K+-ATPase inhibitor (IC50 of 3.1±0.4 μM).
Targets&IC50
H+, K+-ATPase:3.1±0.4 μM
In vitro
Picoprazole is a specific inhibitor of H+/K+-ATPase and binds to 100-kDa polypeptides of the enzyme, dose dependently inhibited opening of the Cl- conductance by Cu2+-o-phenanthroline, indicating that the Cl- conductance is part of the function of the H+/K+-ATPase[2].
Chemical Properties
Molecular Weight343.4
FormulaC17H17N3O3S
Cas No.78090-11-6
Relative Density.1.41g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Picoprazole
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