Shopping Cart
- Remove All
Your shopping cart is currently empty
Platencin
😃Good
Catalog No. T38125Cas No. 869898-86-2
Platencin is a natural, broad-spectrum Gram-positive antibiotic isolated from *S. platensis*, which is also the source of platensimycin. Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic-resistant bacterial strains, including methicillin-resistant *S. aureus*, vancomycin-intermediate *S. aureus*, and vancomycin-resistant Enterococci. For these reasons, platencin has potential applications in fighting antibiotic-resistant bacteria.
Platencin
😃Good
Catalog No. T38125Cas No. 869898-86-2
Platencin is a natural, broad-spectrum Gram-positive antibiotic isolated from *S. platensis*, which is also the source of platensimycin. Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic-resistant bacterial strains, including methicillin-resistant *S. aureus*, vancomycin-intermediate *S. aureus*, and vancomycin-resistant Enterococci. For these reasons, platencin has potential applications in fighting antibiotic-resistant bacteria.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $990 | 35 days | |
| 500 μg | $2,960 | 35 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Platencin is a natural, broad-spectrum Gram-positive antibiotic isolated from *S. platensis*, which is also the source of platensimycin. Platencin inhibits two key enzymes in bacterial fatty acid synthesis, β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively), unlike platensimycin which only targets FabF. The IC50 values for platencin against FabF and FabH are 1.95 and 3.91 μg/ml, respectively. It does not exhibit cross-resistance to antibiotic-resistant bacterial strains, including methicillin-resistant *S. aureus*, vancomycin-intermediate *S. aureus*, and vancomycin-resistant Enterococci. For these reasons, platencin has potential applications in fighting antibiotic-resistant bacteria. |
| Molecular Weight | 425.481 |
| Formula | C24H27NO6 |
| Cas No. | 869898-86-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: Soluble DMF: Soluble Ethanol: Soluble Methanol: Soluble |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Platencin | purchase Platencin | Platencin cost | order Platencin | Platencin chemical structure | Platencin formula | Platencin molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.