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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | Pomalidomide-5-O-CH3, a derivative of Pomalidomide, serves as a specific ligand for cereblon (CRBN) protein recruitment. It can be linked to the protein ligand to create a PROTAC. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Pomalidomide-5-O-CH3 |
Molecular Weight | 303.274 |
Formula | C14H13N3O5 |
Cas No. | 1547163-02-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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