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Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating a cereblon ligand derived from Pomalidomide and a linker commonly used in PROTAC technology.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating a cereblon ligand derived from Pomalidomide and a linker commonly used in PROTAC technology. |
In vitro | PROTACs consist of two ligands linked together: one targeting an E3 ubiquitin ligase and the other targeting the designated protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs enable the selective degradation of target proteins[2]. |
Alias | Pomalidomide-C4-NH2 hydrochloride |
Molecular Weight | 380.83 |
Formula | C17H21ClN4O4 |
Cas No. | 2162120-73-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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